Medicinal Leeches Hirudin
Details of Hirudin:
Product name: Hirudin
Source: Leech
Appearance: brown yellow powder
CAS: 113274-56-9
MF: C66H93N13O25
MW: 1468.53
Certificate of Analysis for Hirudin:
| Product name | Hirudo extract, leech extract | Appearance | Brown to white powder |
| Specification | 25:1,100:1,200:1 800IU/g hirudin | Active ingredient | hirudin |
| Part | Whole dried body | Test method | UV |
| Extraction type | Solvent extraction | Grade | medical grade |
| Brand | Realin | Odor | Characteristic |
| Package | 1kg/bag,25kg/drum. Or as per your requirement | ||
| Storage | Store in cool, dry and clean. Keep from straight light. | ||
| Delivery | Within 1-3 days after payment. | ||
Introduction of Hirudin:
Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (such as Hirudo medicinalis) that has a blood anticoagulant property. This is fundamental for the leeches’ alimentary habit of hematophagy, since it keeps the blood flowing after the initial phlebotomy performed by the worm on the host’s skin.
Function of Hirudin:
1.Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property. This is fundamental for the leeches’ alimentary habit of hematophagy, since it keeps the blood flowing after the initial phlebotomy performed by the worm on the host’s skin.
2.Thrombin is produced from prothrombin, by the action of an enzyme, prothrombinase, in the final states of coagulation. Fibrin is then cross linked by factor XIII to form a blood clot. The principal inhibitor of thrombin in normal blood circulation is antithrombin III.
3.Similar to antithrombin III, the anticoagulatant activity of hirudin is based on its ability to inhibit the pro-coagulant activity of thrombin.Hirudin is the most potent natural inhibitor of thrombin. Unlike antithrombin III hirudin binds to and inhibits only the activity of thrombin forms with a specific activity against fibrinogen.
4.Therefore, hirudin prevents or dissolves the formation of clots and thrombi (i.e. it has a thrombolytic activity), and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins, as a topical application cream. In some aspects, hirudin has advantages over more commonly used anticoagulants and thrombolytics, such as heparin, as it does not interfere with the biological activity of other serum proteins and can also act on complexed thrombin.
Remarks:
1. Delivery time: Prompt delivery by Air Courier, like EMS,DHL,TNT,Fedex after payment confirmed;
2. Product warranty: 24months;
3. Minimum Order Quantity: 1 Kilogram;
4. Payment Terms: 100% advance payment by L/C, T/T, Western Union, MoneyGram, Paypal
5. Supply Ability：5000kgs/month
